
How Long Does Vardenafil Stay in Your System? – Complete guide
Key Takeaways
- Vardenafil is one of the prescription drugs used to treat erectile dysfunction (ED).
- Vardenafil generally begins working within 10 minutes; however, it can also take approximately one hour for the drug to completely take effect.
- Vardenafil’s effects can last an average of 5 to 7 hours.
- The average half-life of Vardenafil is between 4 to 5 hours.
- Vardenafil works if there is sexual stimulation.
- If an erection persists longer than 4 hours, seek medical attention.
How Long Does Vardenafil Stay in Your System?
Vardenafil is another name for a medication that helps men with erectile dysfunction. It is a drug within the PDE5 inhibitor group that allows for better blood flow to the penis while there is stimulation.
The noticeable effects of Vardenafil can last in the body’s system for 5 to 7 hours. Vardenafil can be detected in the body for a much longer time period, even after it has stopped being effective. It takes 4 to 5 hours for the body to completely process half of the Vardenafil leaving the body.
The amount of time it takes for Vardenafil to leave the body is based on several factors, including:
- The individual’s metabolism
- Kidney and liver function
- The specific dosage
- Other medications the individual may be taking
How Long Does Vardenafil Take to Work?
In most cases, Vardenafil starts to have noticeable effects after 1 hour, but some studies have shown that it can take as little as 10 minutes for certain individuals. For this reason, most physicians recommend taking Vardenafil about an hour before sexual activity.
Vardenafil will not generate an erection without sexual stimulation.
Eating a high-fat meal can change the absorption of the medication, so following the instructions for your prescription is critical.
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How Long Does Vardenafil Last?
Many patients experience symptoms of vardenafil after approximately 5 to 7 hours, though this does not signify that the drug is continuously acting throughout this entire time period.
The erection will not be sustained throughout this time, rather vardenafil acts during this time period to facilitate the response to sexual stimulation.
After its active period, the drug will gradually begin to lose its effect once the body has metabolized it.
It is important to note that being able to notice the effects of a drug does not mean that it is completely out of your system as vardenafil can still be present in your body.
How Does Vardenafil Work?
Vardenafil acts on the PDE5 enzyme to enable the persistence of cyclic GMP and therefore help relax the smooth muscle of the blood vessels. The blood vessels of the penile muscles will subsequently relax, and as you are sexually aroused, blood will be able to flow into the penile muscles.
To put it simply, during the stimulation of sexual activity, blood flow will increase, and you will be able to sustain an erection. The medication will support the natural response of the body, and will not cause an erection.
Is Vardenafil Better Than Viagra?
Both vardenafil and sildenafil (Viagra) have the same function and will not be better or worse for any condition.
Feature | Vardenafil | Viagra (Sildenafil) |
Drug class | PDE5 inhibitor | PDE5 inhibitor |
Possible onset | As little as 10 minutes | Around 30 minutes |
Full effect | About 1 hour | About 1 hour |
Typical duration | 5–7 hours | 4–8 hours |
Sexual stimulation needed | Yes | Yes |
Both medications are effective. Your healthcare provider may recommend one of the medications as treatment based on your general health, other medications you are taking, side effects, and your treatment response.
Is Vardenafil Better Than Tadalafil?
Tadalafil is another PDE5 inhibitor, but it has significantly longer effects than vardenafil vs tadalafil.
Feature | Vardenafil | Tadalafil |
Drug class | PDE5 inhibitor | PDE5 inhibitor |
Typical onset | Around 10–60 minutes | Around 30 minutes |
Typical duration | 5–7 hours | Up to 36 hours |
Sexual stimulation needed | Yes | Yes |
Vardenafil is preferred by those looking for a shorter acting medication for planned sexual activity, while others may be better suited with the extended effects of Tadalafil.
Longer effects do not always equate to being better. It is important to consider your symptoms and your medical history.
What Can Affect How Long Vardenafil Stays in Your Body?
Some things that may influence how long it takes for your body to remove the medication are:
- Age: Older adults may take longer to process medications.
- Liver Issue: Clearance of the medication will be slower because it is predominantly metabolized in the liver.
- Medications: Some medications can increase the levels of vardenafil in the blood.
- Dose: Increasing the dose may lead to more side effects.
- Renal Issues: Kidney issues will also affect the removal of the medications from the body.
As you can see, vardenafil has a few unique side effects and situations in which it isn’t recommended to use. Because of that, do not adjust your dose without talking to your doctor first.
Common Side Effects of Vardenafil
Vardenafil usually doesn’t cause serious problems for most people with minor side effects being common. Some of the most reported side effects are:
- Headache
- Flushing
- Stuffy or runny nose
- Dizziness
- Stomach discomfort
There are certain medications that can interact negatively with Vardenafil. The biggest concern is using Vardenafil with medications containing nitrates because this can very quickly and severely lower blood pressure.
Make sure you tell your doctor about all your prescription medications, over the counter drugs, and supplements.
Can You Make Vardenafil Leave Your System Faster?
There isn’t a way to make vardenafil leave your system faster. Drinking lots of water, exercise, or taking supplements won’t speed up elimination in a safe way.
Time is the best way for your body to get vardenafil out of your system. If you’re concerned about how long it takes to get vardenafil out of your system, especially if you have issues with your liver or kidneys, or you have other medications, talking with a healthcare professional is the best way to find out how long vardenafil will stay in your body.
Final Words
Vardenafil remains effective for 5 to 7 hours. This means that most men experience effects for this duration, but the drug remains present in the body for longer. Some men report feeling the effects of the drug after 10 minutes, with maximum effects occurring an hour after ingestion.
Vardenafil’s effects generally last as long as Viagra, while tadalafil lasts longer. The choice of drug is dictated by your doctor based on your specific case, your health, your aims of treatment, and the drugs you are on and the response of your body to treatment.
Seek emergency care for a sustained erection to avoid serious damage that could possibly lead to the inability to obtain erections in the future.




